{"id":1483,"date":"2026-10-05T10:47:52","date_gmt":"2026-10-05T02:47:52","guid":{"rendered":"https:\/\/extruder-lab.com\/?p=1483"},"modified":"2026-10-10T15:28:29","modified_gmt":"2026-10-10T07:28:29","slug":"htgd-series-hot-melt-extruder","status":"publish","type":"post","link":"https:\/\/extruder-lab.com\/es\/htgd-series-hot-melt-extruder.html","title":{"rendered":"Extrusora de fusi\u00f3n en caliente de la serie HTGD: soluci\u00f3n para la dispersi\u00f3n de s\u00f3lidos"},"content":{"rendered":"<p class=\"wp-block-paragraph\">En la 8.\u00aa Exposici\u00f3n de la Industria Farmac\u00e9utica de China (CMC-CHINA), celebrada del 4 al 5 de septiembre de 2026 en el Centro Internacional de Exposiciones de Suzhou, Hartek Technology present\u00f3 su extrusora de doble husillo de fusi\u00f3n en caliente de grado farmac\u00e9utico de la serie HTGD en el stand E-B13. La empresa complet\u00f3 con \u00e9xito la validaci\u00f3n del proceso de extrusi\u00f3n en caliente (HME) de la copovidona VA64 con un principio activo (proceso simulado), produciendo muestras cristalinas con excelente uniformidad y resultados de disoluci\u00f3n.<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img fetchpriority=\"high\" decoding=\"async\" width=\"1024\" height=\"768\" src=\"https:\/\/extruder-lab.com\/wp-content\/uploads\/2026\/09\/6aa26c9505a8d.webp\" alt=\"HTGD Series Hot-Melt Extruder\" class=\"wp-image-1484\"\/><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>Descripci\u00f3n general de la extrusora de termofusible<\/strong><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">La serie HTGD es una extrusora de doble husillo co-rotatorio en paralelo para material termofusible, dise\u00f1ada espec\u00edficamente para aplicaciones farmac\u00e9uticas. Su configuraci\u00f3n de husillos entrelazados proporciona una mezcla altamente eficiente, lo que garantiza una excelente dispersi\u00f3n del f\u00e1rmaco y tiempos de residencia cortos, factores cr\u00edticos para la producci\u00f3n de dispersiones s\u00f3lidas de alta calidad.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>Caracter\u00edsticas principales<\/strong><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\"><em>Ca\u00f1\u00f3n de dos piezas:<\/em> El tambor se puede abrir r\u00e1pidamente para su limpieza, lo que elimina las zonas muertas en las que podr\u00eda quedar material. Este dise\u00f1o reduce significativamente el tiempo de cambio de producto y facilita el cumplimiento de los estrictos requisitos de limpieza de las buenas pr\u00e1cticas de fabricaci\u00f3n (GMP).<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><em>Dise\u00f1o modular del tornillo:<\/em> Los elementos del tornillo son totalmente modulares, lo que permite un ajuste flexible del ensamblaje del tornillo para adaptarse a diferentes API y sistemas de excipientes. Esta adaptabilidad hace que la serie HTGD sea adecuada para una amplia gama de formulaciones, desde las primeras etapas de investigaci\u00f3n y desarrollo hasta la fabricaci\u00f3n a escala industrial.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><em>Sistema de control avanzado:<\/em> El equipo cuenta con un sistema de control PLC de Siemens, lo que permite almacenar recetas y recuperarlas con un solo clic. Los par\u00e1metros del proceso son totalmente rastreables y reproducibles, lo que garantiza una calidad constante del producto en todos los lotes.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><em>Construcci\u00f3n conforme a las buenas pr\u00e1cticas de fabricaci\u00f3n (GMP):<\/em> Dise\u00f1ado de acuerdo con los principios de las buenas pr\u00e1cticas de fabricaci\u00f3n (GMP), todos los componentes que entran en contacto con el producto est\u00e1n fabricados con acero inoxidable de grado alimenticio, lo que garantiza una f\u00e1cil limpieza y mantenimiento.<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" width=\"1024\" height=\"768\" src=\"https:\/\/extruder-lab.com\/wp-content\/uploads\/2026\/09\/6aa26e755a852.webp\" alt=\"HTGD Series Hot-Melt Extruder\" class=\"wp-image-1488\" srcset=\"https:\/\/extruder-lab.com\/wp-content\/uploads\/2026\/09\/6aa26e755a852.webp 1024w, https:\/\/extruder-lab.com\/wp-content\/uploads\/2026\/09\/6aa26e755a852-300x225.webp 300w, https:\/\/extruder-lab.com\/wp-content\/uploads\/2026\/09\/6aa26e755a852-768x576.webp 768w, https:\/\/extruder-lab.com\/wp-content\/uploads\/2026\/09\/6aa26e755a852-16x12.webp 16w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>Resultados de la validaci\u00f3n del proceso<\/strong><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">En la validaci\u00f3n in situ, el <strong><a href=\"https:\/\/extruder-lab.com\/es\/products\/lab-hot-melt-extruder\/\">Extrusora de fusi\u00f3n en caliente HTGD<\/a><\/strong> En esta serie, se mezcl\u00f3 minuciosamente el VA64 con un excipiente simulado por API, lo que dio como resultado una muestra uniformemente transparente, sin separaci\u00f3n de fases ni precipitaci\u00f3n. Estos resultados demostraron la estabilidad del proceso del equipo en la preparaci\u00f3n de dispersiones s\u00f3lidas, as\u00ed como su desempe\u00f1o en cuanto a la precisi\u00f3n del control de temperatura y la facilidad de operaci\u00f3n.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>Acerca de Hartek Technology<\/strong><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Hartek Technology es una empresa nacional de alta tecnolog\u00eda que cuenta con m\u00e1s de 30 patentes nacionales y cuenta con las certificaciones ISO 9001 y CE de la UE. Sus actividades abarcan los sectores del empaque, la agricultura, la industria, los alimentos, el tabaco, la salud, los materiales especializados y la electr\u00f3nica de nuevas energ\u00edas, lo que cubre ocho sectores principales.<\/p>","protected":false},"excerpt":{"rendered":"<p>At the 8th CMC-CHINA China Pharmaceutical Industry Expo, held from September 4 to 5, 2026, at the Suzhou International Expo Center, Hartek Technology showcased its HTGD series pharmaceutical-grade twin-screw hot-melt extruder at booth E-B13. The company successfully completed a hot-melt extrusion (HME) process validation of copovidone VA64 with an API (simulated process), producing crystal-clear samples [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":1484,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"disabled","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[11],"tags":[45],"class_list":["post-1483","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-product-introduction","tag-hot-melt-extruder"],"_links":{"self":[{"href":"https:\/\/extruder-lab.com\/es\/wp-json\/wp\/v2\/posts\/1483","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/extruder-lab.com\/es\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/extruder-lab.com\/es\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/extruder-lab.com\/es\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/extruder-lab.com\/es\/wp-json\/wp\/v2\/comments?post=1483"}],"version-history":[{"count":6,"href":"https:\/\/extruder-lab.com\/es\/wp-json\/wp\/v2\/posts\/1483\/revisions"}],"predecessor-version":[{"id":1512,"href":"https:\/\/extruder-lab.com\/es\/wp-json\/wp\/v2\/posts\/1483\/revisions\/1512"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/extruder-lab.com\/es\/wp-json\/wp\/v2\/media\/1484"}],"wp:attachment":[{"href":"https:\/\/extruder-lab.com\/es\/wp-json\/wp\/v2\/media?parent=1483"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/extruder-lab.com\/es\/wp-json\/wp\/v2\/categories?post=1483"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/extruder-lab.com\/es\/wp-json\/wp\/v2\/tags?post=1483"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}